BDBM191601 3-(2-(4-chlorophenyl)acetamido)isonicotinic acid (N16)

SMILES OC(=O)c1ccncc1NC(=O)Cc1ccc(Cl)cc1

InChI Key InChIKey=BGMIWCIVXVXHDU-UHFFFAOYSA-N

Data  10 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191601   

TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Emory University

LigandPNGBDBM191601(3-(2-(4-chlorophenyl)acetamido)isonicotinic acid (...)
Affinity DataIC50:  177nMpH: 7.2 T: 2°CAssay Description:Reactions were performed in 50 mM HEPES [pH 7.2 for KDM5 or pH 7.5 for KDM4A(1-350)] containing 0.01% BSA and 0.01% Tween-20. To each well, 3 μL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Emory University

LigandPNGBDBM191601(3-(2-(4-chlorophenyl)acetamido)isonicotinic acid (...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of N-terminal his6-tagged human KDM5B (1 to 769 residues) expressed in sf9 insect cells incubated for 20 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed